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Understanding Dupuytren’s Contracture And Treatment

  • By Proliance Southwest Seattle Orthopedics’, Roger M. Blauvelt, MD
  • A guide to Dupuytren’s contracture
  • What causes those lumps and cords in your palm, how the condition progresses, and the full range of treatment options available today
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My fingers are drawing down into my palm — what’s happening?

A guide to Dupuytren’s contracture: what causes those lumps and cords in your palm, how the condition progresses, and the full range of treatment options available today.

Every week, patients come into our clinic with the same puzzling problem: lumpy cords appearing in their palm for no obvious reason, slowly pulling their fingers downward. If this sounds familiar, you may be dealing with a condition called Dupuytren’s contracture.

The good news is that it’s well understood, manageable, and — depending on how far it has progressed — treatable with options ranging from a brief office procedure to surgery. Understanding Dupuytren’s symptoms early helps guide care. Here is what you need to know.

What is Dupuytren’s contracture?

Dupuytren’s contracture is a progressive condition in which abnormal fibrous tissue develops in the palm of the hand and gradually pulls one or more fingers into a permanently bent position. It most commonly affects the ring and small fingers, and can develop in both hands — though not always evenly. The primary cause is an inherited tendency for the palmar fascia to thicken and form cords; while the exact trigger is unclear, genetics play a major role, and certain medical conditions may be associated.

The condition tends to appear at age 50 or older and is significantly more common in men than women. It is most frequently seen in people of Northern European descent and carries a strong genetic component — it often runs in families, passed from parent to child. People with a family history, diabetes, tobacco or alcohol use, or prior hand surgery may be at higher risk for developing Dupuytren’s contracture.

Note: Despite what many patients assume, Dupuytren’s contracture is rarely caused by injury or overuse. It can be associated with certain medical conditions, but in most cases it develops without any clear external trigger.

How does the condition progress?

Initially, the changes in the hand are barely noticeable — perhaps a small dimple or thickening in the palm. Early Dupuytren’s symptoms include a firm nodule, skin puckering, and a feeling that the palm is tightening. Over time, the disease almost always advances:

  •  Fingers are pulled progressively farther into the palm.
  •  Lumps and nodules can form and grow along the cords.
  •  The skin may pit or pucker where the cord attaches.
  •  Multiple fingers can become involved.

Fortunately, Dupuytren’s contracture is usually not painful. Patients complain mainly that the hand feels awkward — it won’t open fully to slip into a pocket or a glove, and the bent finger gets in the way of everyday tasks. Left untreated for years, the contracture can become quite significant. As a general rule, the younger you are when the process begins, the more likely it is to become a significant problem over time.

There is currently no proven way to prevent Dupuytren’s contracture or to stop it from progressing. Maintaining general hand health is sensible, but there is no known preventive therapy; monitoring and timely Dupuytren’s contracture treatment are key.

Treatment Options

Treatment is generally not recommended in the early stages, when the contracture is mild and function is not significantly affected. Once the fingers begin to interfere with daily activities, three main options are available. The goal of all of them is the same: to release or remove the abnormal fibrous cord.

It is important to understand that these cords are not tight tendons. They are abnormal fibrous tissue — dense, strong bands of collagen — and the aim of treatment is to break up or eliminate those bands.

Option 1: Open Surgery (Fasciectomy)

The traditional, most established approach. Incisions allow the surgeon to directly identify and remove the abnormal tissue, untethering the finger(s). Recovery is measured in weeks to several months; hand therapy is often part of the process. After surgery, targeted Dupuytren’s contracture hand therapy helps restore motion and reduce stiffness.

Option 2: Needle Aponeurotomy

A minimally invasive office procedure. Under local anesthetic, a small hypodermic needle is used to puncture and divide the fibers of the cord, releasing the contracture. Most patients return to near-normal activity within days. Follow-up Dupuytren’s contracture hand therapy can optimize outcomes.

Option 3: Collagenase Injection (Xiaflex®)

An FDA-approved injectable enzyme that breaks down the collagen fibers in the cord. Injected directly into the cord, it weakens the tissue so that a stretching procedure — performed a day or two later — can straighten the finger. More than one treatment cycle may be needed. Many patients refer to this as Xiaflex Dupuytren’s; Xiaflex Dupuytren’s is a nonsurgical option that fits well for appropriate cords.

Since the disease was first described in the 1800s, open surgery was long considered the gold standard. Needle aponeurotomy and collagenase injection have both become well-established additions to the toolkit. Each has trade-offs in terms of recovery time, recurrence rate, and suitability for a given patient’s anatomy and disease pattern.

Can Dupuytren’s contracture be cured or prevented?

No treatment currently available cures Dupuytren’s contracture. The underlying tendency to form abnormal tissue persists, and the contracture can recur — in previously treated areas or in new ones. There is no proven way to prevent the condition, although managing general health and avoiding smoking may help overall hand function. The goal of treatment is to control the process as effectively as possible and restore function.

This is why an ongoing relationship with a hand specialist matters. Monitoring the condition over time allows treatment to be timed appropriately and adjusted as the disease evolves.

Getting an evaluation

Because Dupuytren’s disease presents differently in every patient — in terms of which fingers are affected, how quickly it progresses, and how much it limits function — there is no one-size-fits-all treatment plan. An experienced hand surgeon will assess the full picture before recommending a course of action tailored to your Dupuytren’s symptoms and goals.

Article authored by Dr. Roger Blauvelt

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